BDBM445209 US10669235, Nintedanib

SMILES COC(=O)c1ccc2c(C(=Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)c(O)[nH]c2c1

InChI Key InChIKey=CPMDPSXJELVGJG-UUDCSCGESA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445209   

TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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US Patent
LigandPNGBDBM445209(US10669235, Nintedanib)
Affinity DataKi:  8.40nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In DepthDetails US Patent